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Bioidentical hormones: Are they safe?

The latest controversy swirling around hormones is a mouthful: "bioidenticals." What's going on?

Updated:
2008-06-26 10:48
Published:
2007-04-01 10:37
By:
Marcia Kaye
Pill Bottle (Spr07)

The hormone conundrum

Bioidentical hormones generally refer to supplements of estrogen, progesterone or testosterone that are chemically identical to the body’s own hormones. They’re usually derived from plant sources, such as Mexican wild yam and soy, unlike traditional hormones, which come from sources such as the urine of pregnant horses and are molecularly different to a woman’s own. Compounding pharmacists mix bioidenticals to order, usually into transdermal creams, based on a doctor’s prescription.

Whether from plants or animals, all hormones must be manipulated in a lab to make them usable by the body, which, technically speaking, renders them all “synthesized.”

A fairy-tale treatment?

You can’t help feeling inspired by a success story like this one from Diana Boyes. A salesperson from Georgetown, Ont., she had been suffering through four years of a hormonal hell of her body’s own making. “I had so many hot flashes a day that I wanted to run around naked,” says Boyes, 50. She also had migraines, itchy skin, mood swings, insomnia and brain fog, but she refused to take synthetic hormone replacement therapy (HRT) because of its heightened health risks.

Then Boyes discovered Suzanne Somers’ books on bioidentical hormones. This is amazing, she thought, and last August she found a doctor who prescribed them for her. Within a week on the treatment, Boyes was a changed woman. “My hot flashes started going away. I was sleeping through the night. The mood swings, joint aches and headaches were gone. I could even remember my appointments.” And, as Somers promised, Boyes felt sexier. She confides, “With this stuff you actually like your husband again.”

 

A happy ending? Well, it would seem so – except this isn’t the end. In fact, medical science is only beginning to explore the efficacy and safety of bioidentical hormone therapy versus traditional hormone therapy. And the controversy is heating up faster than a 50-year-old in a polyester turtleneck.

Infomercial queen Somers, whose latest book, Ageless: The Naked Truth about Bioidentical Hormones, came out last fall, sees bioidenticals as a fountain of youth.

But a group of seven physicians (some of whom appear in the book) charges publicly that Somers’ recommendations are misleading and even dangerous. Some people say there’s no scientific evidence that bioidenticals are unsafe – which is true. Others counter there’s no proof that they’re safe, either – which is also true. Some argue there’s no national regulation, either in Canada or the U.S., for custom-compounded bioidentical hormones – and that’s true too. One big multinational drug company is pushing hard to get them off the market – but then, that company has seen its own sales of synthetic hormones drop dramatically.

It’s all enough to make the average midlife woman think, Is it hot in here? Or am I caught in the middle of a fiery debate where I’m going to get burned?

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Pagination Documents

Page 1:
The hormone conundrum
Page 2:
Bioidenticals: proponents and critics
Page 3:
Decision-making around hormone therapy a minefield

Comments

  • sum1961's avatar sum1961 wrote:

    2009-10-09 8:23 AM

    You know what bothers me about this is that the whole system doesn't mind doling out anti depressants and such things without testing. You say I'm tired all the time it seem like I sleep but why am I so tired all the time. You must be depressed and hand out a 'happy pill'. I don't know many people who are not on them as a matter of fact and no one seems to be questioning this. Well I am a crazy midlife woman who is looking for answers that don't always involve depression and otherwise. And don't tell me I don't feel what I feel. It seems a majority of women have the same complaints and yet we know nothing about it. With mixed messages about everything out there..........what are we to do. Frustrated at 48
  • lulu44's avatar lulu44 wrote:

    2009-11-11 7:58 AM

    I would like to make a comment about Vanderhaeghe's scoff that a 70 year old women who has taken hormones will look as old as one who hasn't.....abosolutely untrue. My mother took estrogen for 10 years and is now 71 and does not in anyway look like other 71 year old women I've seen. The majority look 20 years her elder and even though my mother is not a small women, she is in stronger and healthier than most 60 year olds I have known. In conclusion, perhaps it would be better for Vanderhaeghe to be careful on the scoffing and take a look around. The proof is out there....just open your eyes!!!!!
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